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IN THE UNITED STATES DISTRICT COURT FOR THE DISTRICT OF MARYLAND _______________________________________ GENZYME CORPORATION, ) Plaintiff, ) ) v. ) ) LUPIN LTD., et al., ) Defendants. ) _______________________________________) ) GENZYME CORPORATION, ) Plaintiff, ) ) v. ) ) IMPAX LABORATORIES, INC. ) Defendant. ) _______________________________________) ) GENZYME CORPORATION, ) Plaintiff, ) ) v. ) ) SANDOZ, INC. ) Defendant. ) _______________________________________) ) GENZYME CORPORATION, ) Plaintiff, ) ) v. ) ) ENDO PHARMACEUTICALS, INC. ) Defendant. ) _______________________________________)

Civil Case No. JFM-09-563 JFM-09-1258 JFM-10-1906

Civil Case No. JFM-09-653 JFM-09-846 JFM-10-1791

Civil Case No. JFM-09-1750 JFM-10-1715

Civil Case No. JFM-09-2589

MEMORANDUM Plaintiff Genzyme Corporation ("Genzyme") has filed an action against defendants Endo Pharmaceuticals Inc., Impax Laboratories Inc., Sandoz Inc., Lupin Ltd., and Lupin

Pharmaceuticals Inc. (collectively, "Defendants") for infringement of United States Patent No. 5,667,775 ("the 775 Patent"). The 775 Patent covers the therapeutic use of phosphate binding "amine polymers" in Genzymes FDA-approved RENAGEL

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Maryland Law